Study of the Impact of the Light-Matter-Interaction on the Human Herpesviruses: A Quantum Field Approach

This contribution describes three self-organized processes of molecules which are infected by the family of human herpesviruses (members of Herpesviridae) whose considered special members are the viruses HSV-1, HSV-2 and HHV-3 (varicella zoster). Th conspicuous effects of these three types of viruses are twofold. First, they are dormant and viable and the most persons even do not notice that they are infected. However, the viruses revive decades later. The effects are shingles which are painful for months or even for years. Other impacts of this herpes family are dermatomes on the thoracic and facial areas (e.g. shut down of eyes or injury of the cornea). The impact of the light on this virus family originates from their location. They reside in the primary sensory neurons of one dorsal root ganglion which is part of the PNS. In contraction to non-infected persons the photoreaction only occurs if the persons are infected. Second, the light matter interaction is described by the laser paradigm which represents a distinguished model of self-organization. This paradigm is applied on two photo-sensitive processes of cancerous molecules that are infected by herpes viruses. The first process concerns the activation of dormant virus encoded growth factors respectively the revival of cancerous polypeptides that originate from the suppressor gene. Such an activation corresponds to the transfer of an electron from the ground state to an exited state by a light field (laser model). The second application of the laser model concentrates to the phototransduction with the emphasis to the signal transduction of second messengers that activate .the transcription factors. Thus, the hypothesis is that he laser model is applicable for both types of processes. All calculations in this contribution are performed in the frame work of the quantum theory of fields, because this approach does not apply only pure mathematical evaluations, but also considers the explicit influence of damping effects and the impact of fluctuating forces. Furthermore, a third simplified process of transduction (convention) is presented which describes the general framework of the transformation of one molecule into another molecule. The recited objectives of this study are outlined by four focal points. First, the elaboration of the dynamics of the proliferation of the herpesviruses, which also includes the threshold when latent cancerous proteins arose to active molecules. Second, the equations of motion, describes also the coherent propagation of wave solutions which spread out much quicker than particle solutions (classical view). Third, the knowledge of the cellular and neural quantum processes during g the propagation of cancerous proteins permits the very early detection of cancer by the novel quantum sensors. Fourth, novel quantum detectors with a very high susceptibility, for example, of magnetic fields (MRT) will be constructed on the background of such quantitative descriptions.