Determining the Relationship between Platelet Indices and Microvascular Complications in Type 2 Diabetic Patients

Diabetes is a common metabolic disorder that affects the global population and is responsible for a significant portion of morbidity and mortality, primarily because of its micro-vascular and macrovascular complications. This is a comparison study that looks at the relationship between platelet indices such as mean platelet volume, platelet distribution width, plateletcrit, and total platelet count in diabetic patients with and without microvascular problems. This review of the literature was carried out using an Internet search on a public access website such as PubMed, Google Scholar, or Medline databases until 2019. The studies that included patients with macrovascular problems and those using medicines that change platelet indices were the main exclusion criteria. All of these articles were analyzed. When compared to those without microvascular difficulties, platelet indices such as mean platelet volume and platelet distribution width were significantly larger in those with microvascular consequences, primarily Diabetic Nephropathy and Diabetic Retinopathy. Diabetic microvascular problems were found to be significantly linked with changes in platelet indices. As a result, these variables can be utilised to monitor and forecast the risk of microvascular problems.