Antimicrobial Activity of Selenium Nanoparticles and Pterocarpus santalinus Based Mouthwash

Introduction: Their unique size-dependent properties make these materials superior and indispensable in many areas of human activity. Selenium possesses excellent photo electrical and semiconductor properties which make it extensively used in duplicate, photography, cells and rectifiers. Selenium is also one of essential trace elements in the human body and has great importance in nourishment and medicine. In India, medicinal plants are widely used by all sections of people either directly as folk remedies or in different indigenous systems of medicine or indirectly in the pharmaceutical preparations of modern medicines. The aim of the present study is to determine antimicrobial activity of selenium nanoparticles and Pterocarpus santalinus based mouthwash.

Materials and Methods: Antimicrobial activity of respective nanoparticles against the strain staphylococcus aureus, Bacillus and E Coli. MH Aagar was utilized for this activity to determine the zone of inhibition. Muller hinton agar was prepared and sterilized for 45 minutes at 120 lbs. Media poured into the sterilized plates and let them stabilize for solidification. The wells were cut using the well cutter and the test organisms were swabbed. The nanoparticles with different concentrations were loaded and the plates were incubated for 24 hours at 37 degree celsius. After the incubation the zones of inhibition were measured.

Results: The highest zones of inhibition were exhibited against two bacterial strains Staphylococcus aureus and Staphylococcus mutans proving that it acts as a good antibacterial against S.aureus and S.mutans infections.