Derivation of Diagnostic Criteria for a Slight Cognitive Impairment Using CKPT (Japanese Version of CWPT): A Recent Study

Objective: CWPT, which is able to detect a slight cognitive impairment in PCSD(Preclinical Stage of Dementia) or MCI(Mild Cognitive Impairment), is attracting attention as a neuropsychological test that allows screening at the stage where we must rely on expensive testing equipment such as PET, MRI and X-CT. CWPT is a test for identifying colors and remembering episodes while reading a story containing Color Words, so it can be easily translated and used in various languages. From the viewpoint of brain function measurement, the initially applied instruments were an electroence-phalograph and a near-inferred spectroscopy. Therefore, the purpose of this paper is to show foreign researchers how to derive the diagnostic criteria in Japan. Methods: Diagnostic criteria were derived by analyzing large-scale data. At this time, since it is impossible to perform MMSE on all the subjects, CKPT was performed after receiving a report that I was normal. As shown in the evidence in the previous paper, the CKPT results show a normal distribution for each age, so a method to check the distribution by subjecting the subjects who disturb the normal distribution of the resulting histogram to trial and error is achieved. Results: The total number of subjects used for the diagnostic criteria was 1325, and 199 subjects were excluded. The average value SD, and the average value 1.5SD were derived as the diagnostic criteria for male and female in their 60s, 70s, and 80s. Conclusion: Using the derived diagnostic criteria, we have gained a foothold to develop various CKPT applications.