Penile Metastasis from Prostate Cancer: A Rare Case

The penis is a rare site of prostate cancer metastasis, the incidence of this metastatic site is less than 0.3%.

We present the case of a 67-year-old man who was consulted after the appearance of a painless red nodule on the penile glans that bled on touch. Digital-rectal examination revealed a nodular and hard prostate, and the PSA level was above 100 ng/ml.

Prostate biopsy confirmed adenocarcinoma Gleason 4+4, and histological examination of the piece resection biopsy of the penile lesion confirmed that it was adenocarcinoma.

MRI of the pelvis showed involvement of the corpus cavernosum and pubic bone by the adenocarcinoma

Bone scintigraphy showed secondary localization to the fourth lumbar vertebra and ischio-pubic branch. The multidisciplinary concerting committee decided on first-line hormonal therapy and chemotherapy.

The patient refused chemotherapy and took only hormonal therapy. We examined him 16 months later. The PSA level was 12 ng/ml , and the penile lesion had completely disappeared.