A Review on Pemphigus

Autoimmune bullous diseases is a heterogeneous group of disorders that is characterized by intraepithelial or sub epithelial blistering caused by formation of autoantibodies targeted against structures essential for integrity of skin and mucous membrane. One such type of autoimmune vesiculobullous disease is Pemphigus, which affects the skin and the mucous membrane. There are different types of pemphigus based on the clinical features, histopathological features and the specific antigens against which autoantibodies have been produced. This review gives an overview on thedifferent types of Pemphigus with its clinical, histopathological and immunopathological characteristics and its treatment.